Every vial is 99%+ purity, verified by third-party HPLC and mass spectrometry, US manufactured, and shipped with a batch-specific Certificate of Analysis. Buy CJC 1295 Ipamorelin blend today: both sizes are in stock, with same-day dispatch on orders placed before 2 PM EST.
CJC-1295 No DAC (also sold as Mod GRF 1-29) is a 29-amino-acid growth hormone releasing hormone (GHRH) analog that signals the pituitary through the GHRH receptor. Ipamorelin is a five-amino-acid growth hormone secretagogue that works through the ghrelin (GHS-R1a) receptor.
Because the two compounds drive growth hormone release through separate pathways, laboratories buy CJC 1295 Ipamorelin blend as a single pre-matched reagent rather than sourcing each peptide separately. Our complete CJC-1295 + Ipamorelin guide covers the full scientific background; the sections below focus on what you receive and how to choose between the 5+5mg and 10+10mg vials.
Select the vial size from the dropdown above. The 5+5mg vial (10mg total peptide) suits pilot studies, first orders, and short single-protocol work. The 10+10mg vial (20mg total peptide) doubles the material in the same sealed format at a lower cost per milligram, which is why most repeat customers buy CJC 1295 Ipamorelin blend in the larger size once a protocol is established.
Ready to buy CJC 1295 Ipamorelin blend? Choose 5+5mg or 10+10mg above, set your quantity, and add to cart. Most researchers also add bacteriostatic water to the same order so the vial is ready for reconstitution on arrival.
Detailed Mechanism of Action
CJC-1295 No DAC binds the GHRH receptor on pituitary somatotrophs, a G-protein-coupled receptor that activates adenylyl cyclase and raises intracellular cAMP. The resulting protein kinase A cascade triggers exocytosis of stored growth hormone and upregulates transcription of the GH gene itself.
The four amino-acid substitutions in the 1-29 sequence (D-Ala2, Gln8, Ala15, Leu27) protect the molecule from dipeptidyl peptidase-IV cleavage and extend its activity to roughly 30 minutes, compared with a few minutes for native GHRH.
Ipamorelin acts on the growth hormone secretagogue receptor (GHS-R1a), the same target as endogenous ghrelin. Receptor activation mobilizes intracellular calcium through the phospholipase C pathway, which amplifies GH release from the same somatotroph population. Ipamorelin also suppresses somatostatin, the hypothalamic brake on GH output, further widening the release window.
Together, the two signals converge on one pulse: the GHRH analog opens the gate, and the secretagogue pushes more hormone through it. Published data on GHRH analogs combined with a GHRP show GH output greater than the sum of either compound alone. Unlike older secretagogues such as GHRP-2 and GHRP-6, Ipamorelin produces negligible cortisol, prolactin, or ACTH release, so the pulse stays specific to the GH axis.
The No DAC version matters for researchers who buy CJC 1295 Ipamorelin blend specifically for pulse studies. Without the Drug Affinity Complex, CJC-1295 clears within hours rather than days, so each administration yields a discrete, measurable peak instead of a sustained elevation that blunts the natural rhythm.
Published Research
Teichman and colleagues (2006) studied CJC-1295 in healthy adults and reported sustained increases in GH and IGF-1 with a favorable tolerability profile, establishing the GHRH-analog approach as a reliable way to raise GH output. Read the full study on PubMed.
Ionescu and Frohman (2006) demonstrated that pulsatile GH secretion persists during stimulation by CJC-1295, with pulse amplitude rising while frequency and timing were preserved. Their JCEM paper is the key citation for why GHRH analogs amplify rather than override the endogenous rhythm.
Raun and colleagues (1998) introduced Ipamorelin as the first selective GH secretagogue, showing potent GH release in vitro and in vivo with no significant effect on ACTH or cortisol at doses that produced a maximal GH response. The original characterization remains the foundation for Ipamorelin’s reputation as the cleanest GHRP.
Researchers who buy CJC 1295 Ipamorelin blend for pulse-amplitude work cite these three papers most often. Our peptide half-life chart summarizes the pharmacokinetic data for both components side by side.
CJC 1295 Ipamorelin Blend vs Alternatives
Researchers comparing GH-axis reagents before they buy CJC 1295 Ipamorelin blend usually weigh it against CJC-1295 with DAC, Sermorelin, and the oral secretagogue MK-677. The table below summarizes the practical differences that matter at the bench and at checkout.
| Feature | This Blend (No DAC + Ipamorelin) | CJC-1295 with DAC | Sermorelin | MK-677 |
|---|
| GHRH component | Yes (Mod GRF 1-29) | Yes (DAC-modified) | Yes | No |
| GHRP component | Yes (Ipamorelin) | No | No | Oral ghrelin mimetic |
| Release pattern | Sharp, pulsatile peaks | Sustained elevation over days | Short, weaker pulse | Continuous elevation |
| Half-life | ~30 min (CJC) / ~2 h (Ipamorelin) | 6–8 days | ~10–20 min | ~24 h |
| Cortisol / prolactin effect | Negligible | Negligible | Negligible | Appetite and cortisol effects reported |
| Two pathways in one vial | Yes | No | No | No |
| Sizes at PSPeptides | 5+5mg and 10+10mg | Varies | Varies | Capsule or liquid |
| Cost per protocol | Lowest when you buy CJC 1295 Ipamorelin blend in 10+10mg | Moderate | Moderate | Higher over long studies |
For a deeper look at the oral alternative, see our MK-677 research guide; for combining this blend with other compounds, our peptide stacking guide walks through common study designs.
Which Size Should You Buy: 5+5mg or 10+10mg?
The right vial depends on how much material a protocol consumes before the reconstituted solution ages out.
A 5+5mg vial reconstituted in 2 mL yields 250 mcg of each peptide per 10 units on a U-100 insulin syringe, or twenty draws at that level per vial. A 10+10mg vial reconstituted in the same 2 mL yields 500 mcg of each peptide per 10 units, or forty draws at the 250 mcg level.
For a single-arm study that draws once or twice daily, the 5+5mg vial is typically exhausted within ten days to three weeks, which fits comfortably inside the recommended 28-day window for reconstituted peptides. Teams that buy CJC 1295 Ipamorelin blend for multi-arm designs, higher-frequency sampling, or two parallel subjects consume the 10+10mg vial on a similar timeline while paying less per milligram.
If you are unsure, buy CJC 1295 Ipamorelin blend in the 5+5mg size first, confirm your draw volumes with the peptide dosage calculator, and move to 10+10mg on your next order. Both sizes come from the same manufacturing line and carry identical purity specifications, so switching does not introduce a new variable into an ongoing study.
Research Protocol Considerations
Most published protocols administer the blend subcutaneously one to three times daily, with the evening administration timed to reinforce the natural nocturnal GH pulse. Because Ipamorelin has a roughly two-hour half-life and CJC-1295 No DAC about 30 minutes, pulses do not stack, and each administration can be treated as an independent event in the dataset.
Many teams run the blend in cycles of eight to twelve weeks followed by a washout, a design discussed in our article on whether peptides need to be cycled.
Plan vial quantities against the cycle length: at 250 mcg of each peptide twice daily, a 5+5mg vial lasts about ten days and a 10+10mg vial about twenty, so an eight-week study needs roughly three 10+10mg vials or six 5+5mg vials. Researchers who buy CJC 1295 Ipamorelin blend for a full cycle usually order the complete quantity up front so every vial is lot-matched.
Reported effects in the literature include transient flushing, injection-site irritation, and water retention. Review our peptide side effects reference when designing observation schedules.
Reconstitution & Handling
Let the vial reach room temperature before opening. Swab the stopper, then add bacteriostatic water slowly down the inside wall of the vial rather than directly onto the powder. Swirl gently until clear; never shake, because shear stress can fragment peptide chains. Full step-by-step instructions are in our guide on how to reconstitute peptides.
| Vial | Water Added | Concentration (each peptide) | 10 Units (0.1 mL) Delivers |
|---|
| 5+5mg | 2 mL | 2.5 mg/mL | 250 mcg CJC-1295 + 250 mcg Ipamorelin |
| 5+5mg | 1 mL | 5 mg/mL | 500 mcg CJC-1295 + 500 mcg Ipamorelin |
| 10+10mg | 2 mL | 5 mg/mL | 500 mcg CJC-1295 + 500 mcg Ipamorelin |
| 10+10mg | 3 mL | 3.33 mg/mL | 333 mcg CJC-1295 + 333 mcg Ipamorelin |
Because both peptides are supplied in one vial at a fixed 1:1 ratio, a single reconstitution yields a solution that delivers equal amounts of each compound per unit drawn.
Verify every draw with the peptide dosage calculator before you begin, and write the concentration on the vial label so colleagues who buy CJC 1295 Ipamorelin blend for the same study use consistent volumes, especially when 5+5mg and 10+10mg vials are in use at the same bench.
Storage & Stability
Lyophilized vials are stable for 24 months or longer at 2–8°C and for extended periods at -20°C. Short excursions to room temperature during shipping do not affect potency; the powder is far more robust than the reconstituted solution. Keep vials in their box to limit light exposure.
This stability is why many labs buy CJC 1295 Ipamorelin blend several vials at a time and hold the sealed stock cold until needed.
After reconstitution with bacteriostatic water, store the vial upright at 2–8°C and use within 28 days. Do not freeze reconstituted solution, as ice crystals can denature the peptides.
Our peptide storage guide and peptide degradation guide explain how to identify compromised material. If you buy CJC 1295 Ipamorelin blend in the 10+10mg size but a protocol will not consume 20mg within four weeks, two 5+5mg vials opened in sequence keep every draw inside the stability window.
Certificate of Analysis
Every batch is tested by an independent laboratory using reverse-phase HPLC for purity and mass spectrometry for identity confirmation. The COA ships with your order and lists the lot number, purity percentage, observed molecular mass for each component, and test date.
Both the 5+5mg and 10+10mg vials are filled from the same qualified bulk material, so when you buy CJC 1295 Ipamorelin blend in either size, the COA references the same lot specifications.
Learn what each line of the report means in our guide to reading a peptide COA. Before you buy CJC 1295 Ipamorelin blend from any supplier, confirm that purity is reported per batch and not as a generic claim; our article on choosing a research peptide supplier lists the questions worth asking.
Why Researchers Choose PSPeptides
- US Manufactured: Produced in a US facility under documented quality procedures.
- Third-Party Tested: Independent HPLC and mass spectrometry on every lot.
- Fast Shipping: Free UPS 2nd Day Air over $200, same-day dispatch before 2 PM EST.
- Flexible Payments: Credit cards, Afterpay, Klarna, Apple Pay, Google Pay.
- 7-Day Support: Email, phone, or text, seven days a week.
Researchers buy CJC 1295 Ipamorelin blend from PSPeptides because the testing is transparent, both sizes stay in stock, and the vial you receive matches the COA in your hand.
What You Receive
Each order includes your selected sealed vial — 5+5mg (10mg total) or 10+10mg (20mg total) — the batch-specific Certificate of Analysis, and a packing slip referencing the lot number for traceability. The vial is packed in a crush-resistant, discreet mailer with no exterior product labeling. When you buy CJC 1295 Ipamorelin blend in multi-vial quantities, all vials ship lot-matched from the same batch whenever possible.
Ordering, Shipping & Payment
Buy CJC 1295 Ipamorelin blend before 2 PM EST Monday through Friday and it leaves our facility the same business day. Domestic shipments travel via UPS, with 2nd Day Air free on orders over $200 and tracking emailed at dispatch. The lyophilized vial travels safely at ambient temperature. Bulk and institutional buyers can request a volume quotation and expedited freight by contacting support before checkout.
Checkout accepts all major credit cards, Apple Pay, and Google Pay, plus Afterpay and Klarna for split payments on larger orders. Combining vials with supplies in one order is the easiest way to reach the $200 free-shipping threshold.
When you buy CJC 1295 Ipamorelin blend alongside bacteriostatic water, syringes, and other supplies, everything ships together in one tracked package. International researchers should confirm local importation rules before ordering; see are research peptides legal in 2026 for an overview of the current regulatory landscape.
Compatible Research Supplies
Most laboratories pair this vial with sterile bacteriostatic water, U-100 insulin syringes (28–31 gauge), alcohol prep pads, and a sharps container. A dosage calculator or shared spreadsheet keeps draw volumes consistent across the team, which matters more once you move from the 5+5mg to the 10+10mg vial and the concentration per unit doubles.
For researchers who prefer a non-injectable format, PSPeptides also stocks a CJC No DAC + Ipamorelin intranasal spray that can be ordered on the same ticket.
An under-counter laboratory refrigerator held at 2–8°C is sufficient for storage. Avoid household freezers, which cycle through wide temperature ranges. If you plan to buy CJC 1295 Ipamorelin blend as part of a larger GH-axis study, our complete guide to peptides and subcutaneous vs intramuscular injection article are useful protocol references.
Frequently Asked Questions
Where can I buy CJC 1295 Ipamorelin blend online?
You can buy CJC 1295 Ipamorelin blend directly from this page in 5+5mg or 10+10mg vials. Select a size, add to cart, and check out with a card, Apple Pay, Google Pay, Afterpay, or Klarna. Orders placed before 2 PM EST Monday through Friday ship the same day with tracking.
What is the difference between the 5+5mg and 10+10mg vials?
Only the quantity. Whether you buy CJC 1295 Ipamorelin blend in 5+5mg or 10+10mg, both contain CJC-1295 No DAC and Ipamorelin at a 1:1 ratio, both are 99%+ purity from the same manufacturing line, and both ship with a batch-specific COA. The 10+10mg vial holds twice the peptide for a lower cost per milligram, which makes it the better choice for longer protocols or multi-arm studies.
What is the difference between CJC-1295 No DAC and CJC-1295 with DAC?
The DAC (Drug Affinity Complex) version binds to albumin and circulates for about a week, producing a sustained GH elevation. The No DAC version in this blend clears within hours, producing a sharp, natural-looking pulse. Researchers who buy CJC 1295 Ipamorelin blend typically want the pulsatile profile, which is why No DAC is paired with Ipamorelin.
Is it cheaper to buy CJC 1295 Ipamorelin blend than two separate vials?
Typically, yes. A pre-mixed vial eliminates the second vial, the second reconstitution, and the risk of ratio errors, and it guarantees an exact 1:1 mix in every draw. The 10+10mg option lowers the price per milligram further compared with the 5+5mg vial.
Can both peptides be reconstituted together in one vial?
They already are. The blend is lyophilized together, so one addition of bacteriostatic water dissolves both peptides into a single homogeneous solution. Both compounds are stable in the same solution at 2–8°C for the standard 28-day window.
How much bacteriostatic water should I add?
Two milliliters is the most common volume for either size. In a 5+5mg vial that gives 2.5 mg/mL of each peptide; in a 10+10mg vial it gives 5 mg/mL of each. Use the dosage calculator to convert your target amount into syringe units, and record the concentration on the vial.
What testing comes with each vial?
Every lot is tested by an independent laboratory using HPLC for purity and mass spectrometry for identity. The batch-specific COA is included in your package, and the lot number on the vial matches the report so results are traceable.
How fast will my order arrive?
Buy CJC 1295 Ipamorelin blend before 2 PM EST Monday through Friday and it ships the same business day via UPS. Orders over $200 qualify for free 2nd Day Air, and tracking is emailed at dispatch, so most US customers receive their vial within a few business days.
Can I buy CJC 1295 Ipamorelin blend in bulk for a laboratory?
Yes. Increase the quantity on this page for standard multi-vial orders, or contact our support team by email, phone, or text for institutional pricing on larger 10+10mg quantities, lot-matched batches, and expedited freight. We can also issue a quotation and COA in advance for procurement review.
Related Resources
All PSPeptides products are sold exclusively for laboratory and research use. Not intended for human consumption.
Made & Shipped
